<code id='14A8070D69'></code><style id='14A8070D69'></style>
    • <acronym id='14A8070D69'></acronym>
      <center id='14A8070D69'><center id='14A8070D69'><tfoot id='14A8070D69'></tfoot></center><abbr id='14A8070D69'><dir id='14A8070D69'><tfoot id='14A8070D69'></tfoot><noframes id='14A8070D69'>

    • <optgroup id='14A8070D69'><strike id='14A8070D69'><sup id='14A8070D69'></sup></strike><code id='14A8070D69'></code></optgroup>
        1. <b id='14A8070D69'><label id='14A8070D69'><select id='14A8070D69'><dt id='14A8070D69'><span id='14A8070D69'></span></dt></select></label></b><u id='14A8070D69'></u>
          <i id='14A8070D69'><strike id='14A8070D69'><tt id='14A8070D69'><pre id='14A8070D69'></pre></tt></strike></i>

          entertainment

          entertainment

          author:knowledge    Page View:6
          mitochondria
          Illustration of mitochondria, powerhouse of the cell. Adobe

          As elite hunters of the immune system, T cells are constantly prowling our bodies for diseased cells to attack. But when they encounter a tumor, something unexpected can happen. New research shows that some cancer cells can fire a long nanotube projection into the T cell that, like a vampire’s fang, sucks energy-creating mitochondria from the immune cell, turning the predator into prey.

          A study published this week in Cancer Cell investigated how cancer cells can rob mitochondria from T cells, shutting the immune cell down while energizing themselves. It may be yet another way cancer overcomes both the body’s defenses and resists many immunotherapies like CAR-T therapy and immune checkpoint blockade drugs, experts said.

          advertisement

          “This is a new mechanism of immune evasion. It seems like the cancer cells are draining mitochondria from the T cells,” said Bo Li, a cancer researcher at the University of Pennsylvania and a senior author on the paper. “It’s really amazing. Some of my colleagues, their reaction was like, ‘I can’t believe this is true.’ I understand that. It’s just like the cancer cell is too smart.”

          Get unlimited access to award-winning journalism and exclusive events.

          Subscribe Log In

          knowledge

          Malaria cases in Florida and Texas: Here’s what you need to know
          Malaria cases in Florida and Texas: Here’s what you need to know

          MosquitoscaughtfortestingawaitshipmenttoalabinMcAllen,Texas,inApril2016tobetestedformosquito-bornedi

          read more
          Data integrity in scientific journals requires "effort" by publishers, institutions
          Data integrity in scientific journals requires "effort" by publishers, institutions

          ScientificwatchdogsSholtoDavid(right)andElisabethBikjoinSTAT'sJonathenWosenattheSTATBreakthroughSumm

          read more
          Supreme Court strikes down use of affirmative action
          Supreme Court strikes down use of affirmative action

          ActivistsdemonstratedastheSupremeCourtheardoralargumentsonapairofaffirmativeactioncasesinOctober2022

          read more

          ADCs take center stage as promising cancer treatments

          AtESMO2023,antibody-drugconjugateswerefeaturedprominently.AndrewJoseph/STATMADRID—Ifyouhadtopinpoint