<code id='A42815756A'></code><style id='A42815756A'></style>
    • <acronym id='A42815756A'></acronym>
      <center id='A42815756A'><center id='A42815756A'><tfoot id='A42815756A'></tfoot></center><abbr id='A42815756A'><dir id='A42815756A'><tfoot id='A42815756A'></tfoot><noframes id='A42815756A'>

    • <optgroup id='A42815756A'><strike id='A42815756A'><sup id='A42815756A'></sup></strike><code id='A42815756A'></code></optgroup>
        1. <b id='A42815756A'><label id='A42815756A'><select id='A42815756A'><dt id='A42815756A'><span id='A42815756A'></span></dt></select></label></b><u id='A42815756A'></u>
          <i id='A42815756A'><strike id='A42815756A'><tt id='A42815756A'><pre id='A42815756A'></pre></tt></strike></i>

          focus

          focus

          author:focus    Page View:7
          close-up of psoriasis on a hand. -- biotech coverage from STAT
          A close-up of psoriasis on a hand. Adobe

          San Francisco startup Alumis Inc. has raised $259 million in a bid to best big pharma’s work in plaque psoriasis.

          Alumis announced its Series C round Wednesday and plans to move its lead drug into Phase 3 trials. Venture firm Foresite Capital, which incubated Alumis, co-led the financing with Samsara BioCapital and venBio Partners.

          advertisement

          Alumis’ lead drug, ESK-001, is an oral medicine designed to help patients with the most common type of psoriasis by inhibiting a signaling protein called TYK2. Research has shown that the TYK2 protein plays a role in diseases where the immune system overreacts, which has made it a popular drug target in recent years.

          Get unlimited access to award-winning journalism and exclusive events.

          Subscribe Log In

          explore

          Hepatitis C has a cure — but many Americans still lack access to it
          Hepatitis C has a cure — but many Americans still lack access to it

          AdobeIn2005,NickVoyleswasdiagnosedwithhepatitisCafterbeingreleasedfromfiveyearsofincarceration.Anurs

          read more
          Advances in CAR
          Advances in CAR

          AdamFeuerstein,upperleft,moderatedapanelwith,clockwise,DavidChangofAllogeneTherapeutics,RachelHaurwi

          read more
          DIEP, the 'gold standard' of breast reconstruction, is under threat
          DIEP, the 'gold standard' of breast reconstruction, is under threat

          AdobeIn1983,Iflewhomefromcollegetobewithmymotherasshewokeupfromamastectomy.Sheoptedoutofbreastrecons

          read more

          Crinetics acromegaly drug succeeds in late

          AresearcherworkinginthelabatCrineticsPharmaceuticalsinSanDiego.CourtesyCrineticsSANDIEGO—CrineticsPh