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Mayo Clinic will spend $5 billion to reinvent its flagship medical campus in Rochester, Minn., infusing digital technologies into several new buildings designed to present a 21st-century vision of clinical care, the organization said Tuesday.

The project, to include five new buildings with 2.4 million square feet of space, will merge Mayo’s traditional medical services with its increasing investments in artificial intelligence and digital tools. The technologies will be embedded into the buildings themselves — rather than tacked on in a clunky way —  with the hope of creating more effective and meaningful interactions between patients and clinicians.

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“It blurs the lines between digital and physical,” Mayo’s chief executive, Gianrico Farrugia, told STAT. Clinical floors will be designed to accommodate inpatient recovery, surgery, and imaging technology, services typically spread across multiple floors. AI and predictive tools will help plan care and hospital operations, and surface escalating risks and emergent clinical problems.

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