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author：explore 2025-09-06 06:20:21 Page View：79

Priscilla Chan, left, with Shana Kelley and Gov. J.B. Pritzker of Illinois at the new CZ Biohub Chicago. Courtesy Dale Ramos/Chan Zuckerberg Initiative

CHICAGO — At what point does inflammation, a key component of the body’s immune defense system, swerve out of control and start to drive disease?

That’s the key question that a new research center, the Chan Zuckerberg Biohub Chicago, has been created to try to answer.

The Chicago hub is the second one started by the Chan Zuckerberg Initiative, the philanthropic organization of Facebook founder Mark Zuckerberg and his wife, Priscilla Chan. The first hub, based in the Bay Area, has been investigating cell biology and infectious diseases, while this new one is homing in on inflammatory processes in tissues across the body.

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