<code id='5CBF8F126F'></code><style id='5CBF8F126F'></style>
    • <acronym id='5CBF8F126F'></acronym>
      <center id='5CBF8F126F'><center id='5CBF8F126F'><tfoot id='5CBF8F126F'></tfoot></center><abbr id='5CBF8F126F'><dir id='5CBF8F126F'><tfoot id='5CBF8F126F'></tfoot><noframes id='5CBF8F126F'>

    • <optgroup id='5CBF8F126F'><strike id='5CBF8F126F'><sup id='5CBF8F126F'></sup></strike><code id='5CBF8F126F'></code></optgroup>
        1. <b id='5CBF8F126F'><label id='5CBF8F126F'><select id='5CBF8F126F'><dt id='5CBF8F126F'><span id='5CBF8F126F'></span></dt></select></label></b><u id='5CBF8F126F'></u>
          <i id='5CBF8F126F'><strike id='5CBF8F126F'><tt id='5CBF8F126F'><pre id='5CBF8F126F'></pre></tt></strike></i>

          Wikipedia

          Wikipedia

          author:explore    Page View:2677
          Representative fluorescent multiplex immunohistochemistry colorful staining of healthy human colon. -- cancer coverage from STAT
          Staining reveals different immune cells in a healthy human colon. Courtesy Olivia Newton-John Cancer Research institute

          Within the linings of our guts, immune cells patrol like sentries on a castle wall. These cells, called intraepithelial T lymphocytes, are constantly probing the cells of the gut barrier for signs of disease, killing any cells that appear suspect due to infections or cancer mutations.

          A new paper published in Science Immunologyon Friday suggests that a subtype of T cells called gamma-delta T cells may be key to that process — and that a protein known as TCF-1 is central to controlling their actions. The work, led by Australian researchers, helps unlock the long underappreciated role of these cells in cancer defense and could open new directions for developing immunotherapies for colorectal cancer, immunologists said.

          advertisement

          Gamma-delta T cells have been “largely understudied” compared to their immune counterparts, alpha-beta T cells, said Ana Carrizosa Anderson, a cancer researcher at Harvard University who did not work on the study. “This study certainly helps cement the role of gamma-delta T cells in colon malignancy,” she said. “I think it provides a foundation for building understanding of some basic biology or some therapeutic approaches.”

          Get unlimited access to award-winning journalism and exclusive events.

          Subscribe Log In

          explore

          How one medical school became remarkably diverse
          How one medical school became remarkably diverse

          ThefirstclassattheUniversityofCalifornia,Davismedicalschool,in1972,waspredominantlywhiteandmale.Chri

          read more
          AI can’t replace a physician’s gut feeling
          AI can’t replace a physician’s gut feeling

          AdobeI’veheard“WebMDsaiditcouldbecancer”countlesstimesinmy15yearsworkingasanemergencymedicinephysici

          read more
          Apple is now the first public company to be valued at $3 trillion
          Apple is now the first public company to be valued at $3 trillion

          6:09FILE-AnApplelogoadornsthefacadeofthedowntownBrooklynApplestoreonMarch14,2020,inNewYork.Applebeca

          read more

          Biden tests positive for Covid

          PresidentJoeBidenremoveshisfacemaskashearrivestospeakduringameetingwithCEOsintheWhiteHousecomplexThu