<code id='70AE75FB27'></code><style id='70AE75FB27'></style>
    • <acronym id='70AE75FB27'></acronym>
      <center id='70AE75FB27'><center id='70AE75FB27'><tfoot id='70AE75FB27'></tfoot></center><abbr id='70AE75FB27'><dir id='70AE75FB27'><tfoot id='70AE75FB27'></tfoot><noframes id='70AE75FB27'>

    • <optgroup id='70AE75FB27'><strike id='70AE75FB27'><sup id='70AE75FB27'></sup></strike><code id='70AE75FB27'></code></optgroup>
        1. <b id='70AE75FB27'><label id='70AE75FB27'><select id='70AE75FB27'><dt id='70AE75FB27'><span id='70AE75FB27'></span></dt></select></label></b><u id='70AE75FB27'></u>
          <i id='70AE75FB27'><strike id='70AE75FB27'><tt id='70AE75FB27'><pre id='70AE75FB27'></pre></tt></strike></i>

          knowledge

          knowledge

          author:entertainment    Page View:66692
          Marian F. Moratinos for STAT

          Enticed by the immense market opened by GLP-1 weight loss drugs Wegovy and Zepbound, a handful of biotech companies are trying to develop next-generation, longer-lasting therapies based on a very different approach: RNA interference.

          This Nobel Prize-winning science works by degrading the biological blueprints that RNA use to make proteins — without the genetic instructions, the troublesome proteins are never made and the gene is essentially muted.

          advertisement

          If the companies succeed, it would be a significant shift in the obesity treatment revolution, away from weekly drugs targeting hormones to medications that could be given much less frequently — twice a year or even less — and pinpoint genetic contributors to weight.

          STAT+ Exclusive Story

          Already have an account? Log in

          STAT+

          This article is exclusive to STAT+ subscribers

          Unlock this article — plus daily coverage and analysis of the biotech sector — by subscribing to STAT+.

          Already have an account? Log in

          Already have an account? Log in

          Monthly

          $39

          Totals $468 per year

          $39/month Get Started

          Totals $468 per year

          Starter

          $30

          for 3 months, then $39/month

          $30 for 3 months Get Started

          Then $39/month

          Annual

          $399

          Save 15%

          $399/year Get Started

          Save 15%

          11+ Users

          Custom

          Savings start at 25%!

          Request A Quote Request A Quote

          Savings start at 25%!

          2-10 Users

          $300

          Annually per user

          $300/year Get Started

          $300 Annually per user

          View All Plans

          Get unlimited access to award-winning journalism and exclusive events.

          Subscribe Log In

          knowledge

          ChatGPT in medicine: STAT answers readers' burning questions
          ChatGPT in medicine: STAT answers readers' burning questions

          MikeReddyforSTATArtificialintelligenceisoftendescribedasablackbox:anunknowable,mysteriousforcethatop

          read more
          Arizona Democrat to raise extreme heat with Biden 1 year out from Senate primary
          Arizona Democrat to raise extreme heat with Biden 1 year out from Senate primary

          1:29Rep.RubenGallego,D-Ariz.,holdsatownhallinBuckeye,Ariz.,Aug.6,ashecampaignsfortheU.S.Senate.ABCNe

          read more
          Wildfire smoke exposes gaps in outdoor worker protections
          Wildfire smoke exposes gaps in outdoor worker protections

          ApersonwaitingforthesubwaywearsafilteredmaskassmokyhazefromwildfiresinCanadablanketsaneighborhoodinN

          read more

          Arizona Democrat to raise extreme heat with Biden 1 year out from Senate primary

          1:29Rep.RubenGallego,D-Ariz.,holdsatownhallinBuckeye,Ariz.,Aug.6,ashecampaignsfortheU.S.Senate.ABCNe